calcium waves การใช้

• It can reduce calcium sparks and thus arrhythmogenic calcium waves in the heart.
• Cortical granule exocytosis has been shown to occur directly following a calcium wave.
• Calcium waves are supported by glial cells, which help maintain and modulate neuronal metabolism.
• Upon electrical stimulation, the transient calcium wave emerges inside the yeast cells and translates into a measurable light signal.
• Furthermore, when calcium waves were suppressed experimentally, cortical granule exocytosis and / or alterations in the extracellular matrix did not occur.
• Calcium waves within the intracellular matrix of the astrocyte can cause a response in microglia with the presence of ATP in the extracellular matrix.
• Astrocytes signal each other using ATP, and consequent activation of purinergic receptors on other astrocytes, may also mediate calcium waves in some cases.
• In mammals, the first calcium wave occurs within 1 4 minutes following fertilization, and cortical granule exocytosis occurs within 5 30 minutes following fertilization.
• Hypothetical roles of pannexins in the nervous system include participating in sensory processing, synchronization between hippocampus and cortex, hippocampal plasticity, and propagation of calcium waves.
• A decreased concentration of oxygen releases ATP from erythrocytes, triggering a propagated calcium wave in the endothelial layer of blood vessels and a subsequent production of nitric oxide that results in vasodilation.
• In addition, P2Y receptors activate inositol trisphosphate, which leads to a transient increase in intracellular calcium, and opens both connexin and pannexin channels, therefore contributing to the propagation of calcium waves across astrocytes and epithelial cells.
• In 2007 he observed that microglial cells of the brain can conduct calcium waves that are mediated by the release of NANC transmitters ( purines ), opening up the study of the interaction of the immune and nervous systems at the level of the synapse.